بررسی عوامل موثر بر لخته داخل دهلیز چپ در بیمارانی که تحت عمل جراحی دریچه میترال قرار گرفته اند

Background and Aim: Rheumatic heart disease (RHD) is a serious health problem in developing countries. Mitral stenosis is one of the most prevalent forms of RHD and one of the causes of systemic thromboembolism in Iran. The present study was conducted to evaluate the relationship between left atrial clot and mitral valve disease. Materials and Methods: This case-control study was done on all patients who had undergone mitral valve surgery during 5 years in Ghaem hospital. Patients who had left atrial thrombus (LAT) were in the case group and patients with no LAT and no history of thromboembolism in the control group. Personal history, clinical examination, electrocardiography (ECG) and Echocardiography (Echo) were compared in the two groups. Then the data were analyzed using SPSS software and statistical χ2and t test. Thus P<0.05 was taken significant level. Results: There was no relationship between sex and LAT [females 45.1% in case, 47.33% in control group, P=0.25]. The patients in the case group were older (mean age in the case 37.24 years, in the control group 32.23 years, P=0.01). Atrial fibrillation (AF) (74.5% in the case, 63% in the control group, P<0.001) and severe mitral stenosis (88.57% in the case, 65.49% in the control group, P=0.25) were risk factors for LAT but severe mitral regurgitation was more in the control group (25.93% in the case, 39.6% in the control group, P=0.05). Conclusion: According to the results of the present study, it is recommended that patients with severe mitral stenosis, AF and at old age take prophylactic anticoagulation so that the risk of thromboembolism would decrease in them.